The study of brain tissue has led to great advances in finding a cure for many neurological diseases, such as Alzheimer and Parkinson. In order to perform medical research, it is necessary to collect ideal brain tissue samples from individuals who are neurologically healthy and unhealthy.

The goal of the University of Wisconsin/Veterans Administration Madison Brain Bank is to provide human brain tissues to researchers doing innovative work in the field of neurodegenerative diseases. After collection and stringent review, brain tissue is made available to researchers not only at the University of Wisconsin-Madison but worldwide.

The Brain Bank in Madison Wisconsin was first established in 1995 and received Institutional Review Board (IRB) approval to collect brain tissue from autopsy and neurosurgical patients to aid scientific research. In 2006, funding from the State of Wisconsin allowed the Brain Bank to expand its scope and become registered as the UW/VA Madison Brain Bank. This expansion allowed the Brain Bank to energetically collaborate with the Wisconsin Alzheimer's Disease Research Center and the Wisconsin Alzheimer’s Institute, as well as to become active in the public domain across the state of Wisconsin.